Research Fellowship

研究奖学金

• 批准号: nhmrc : 1021148
• 负责人: Prof Carola Vinuesa
• 金额: $ 45.06万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/research-fellowship/110094
• 关键词: Research; Fellowship

I am an immunologist focusing on understanding how can we combat chronic infections while preventing autoimmunity. This proposal aims to investigate how a poorly understood subset of lymphocytes called Tfh cells are regulated to promote the formation of protective antibodies, and prevent development of harmful antibodies that go on to cause or exacerbate diseases such as lupus, rheumatoid arthritis and type 1 diabetes. Our discoveries will illuminate novel drug targets for these diseases and help generate more potent vaccines.

我是一名免疫学家，专注于了解我们如何在预防自身免疫的同时抗击慢性感染。这项提议旨在研究如何调节一种鲜为人知的淋巴细胞亚群，即TFH细胞，以促进保护性抗体的形成，并防止有害抗体的发展，这些抗体会导致或加剧狼疮、类风湿性关节炎和1型糖尿病等疾病。我们的发现将阐明这些疾病的新药物靶点，并有助于生产更有效的疫苗。