Genetic pathology of Roquin in human autoimmune disease
Genetic pathology of Roquin in human autoimmune disease
批准号:
nhmrc : 471439
负责人:
Prof Carola Vinuesa
金额:
$33.04万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2010-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Lupus is a life-threatening disease in which immune responses normally targeted at germs are directed at tissue in the body. We have discovered a mouse model of lupus and elucidated an important pathway that determines whether immunity is directed at the body or at germs. Building on recent progress in understanding the genetic variation between individuals, we will use the information obtained from the mouse model to investigate the genes that regulate this pathway in people with lupus.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Control of pathogenic antibody responses in humans
-
批准号:nhmrc : 1117812
-
项目类别:Research Fellowships
-
资助金额:$52.22万
-
财政年份:2017
-
负责人:Prof Carola Vinuesa
-
依托单位:
Control of pathogenic antibody responses in humans
-
批准号:nhmrc : GNT1117812
-
项目类别:Research Fellowships
-
资助金额:$76.38万
-
财政年份:2017
-
负责人:Prof Carola Vinuesa
-
依托单位:
Uncovering the basis of inflammatory and immunodeficiency diseases
-
批准号:nhmrc : GNT1016953
-
项目类别:Programs
-
资助金额:$1571.81万
-
财政年份:2012
-
负责人:Prof Carola Vinuesa
-
依托单位:
Research Fellowship
-
批准号:nhmrc : 1021148
-
项目类别:Research Fellowships
-
资助金额:$45.06万
-
财政年份:2012
-
负责人:Prof Carola Vinuesa
-
依托单位:
Molecular and cellular basis of inflammatory and immunodeficiency diseases
-
批准号:nhmrc : 1016953
-
项目类别:Program Grants
-
资助金额:$1123.27万
-
财政年份:2012
-
负责人:Prof Carola Vinuesa
-
依托单位:
The role of Roquin in microRNA function and decay
-
批准号:DP110100422
-
项目类别:Discovery Projects
-
资助金额:$40.5万
-
财政年份:2011
-
负责人:Prof Carola Vinuesa
-
依托单位:
Defining the immunoregulatory function of Roqin: a novel gene essential for preventing autoimmunity
-
批准号:nhmrc : 316956
-
项目类别:NHMRC Project Grants
-
资助金额:$48.09万
-
财政年份:2005
-
负责人:Prof Carola Vinuesa
-
依托单位:
Translational study of the genetics of systemic autoimmunity based on mouse mutagenesis
-
批准号:nhmrc : 316914
-
项目类别:NHMRC Project Grants
-
资助金额:$34.57万
-
财政年份:2005
-
负责人:Prof Carola Vinuesa
-
依托单位:
Mechanisms controlling antibody production by modulating B cell antigen receptor signalling
-
批准号:nhmrc : 224264
-
项目类别:NHMRC Project Grants
-
资助金额:$30.15万
-
财政年份:2003
-
负责人:Prof Carola Vinuesa
-
依托单位:
海外基金