Development of affect processing and regulation: an electrocortical approach

情感处理和调节的发展：电皮层方法

• 批准号: 203710-2011
• 负责人: Schmidt, Louis
• 金额: $ 2.28万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=477257
• 关键词: Development; affect; processing; regulation; electrocortical

The appraisal, regulation, and expression of emotion play important roles in the motivational and communicative aspects of human behaviour and are critical to optimal human development. All of the Axis II disorders described in the Diagnostic and Statistical Manual for Mental Disorders (DSM-IV, American Psychiatric Association, 1994, e.g., depression, anxiety, conduct disorder) list an inability to regulate negative affect as a criterion for diagnosis. We know, however, comparatively little in terms of the development of affect processing and regulation in children. A first step in understanding how children regulate emotion is to understand how they process emotion. The primary goal of my NSERC-funded research program is to examine the development of affect processing and regulation in typically developing children during the first four years of life. In a series of recent NSERC-funded studies, we found distinct patterns of frontal lobe and autonomic activity during the processing of different types of affective auditory and visual stimuli in human infants and adults. The proposed NSERC grant period will allow us to continue and extend our work examining the development of affect processing and regulation in typical human development to older children and young adults. We will: 1) in our initial studies, recruit separate cohorts of young adults in order to refine our measures and to extend our previous developmental work to adults, 2) recruit cross-sectional cohorts at developmental time points in early childhood, and recruit a separate cohort of 24-month-old children to follow longitudinally and test at the same time-points as the cross-sectional cohorts, in order to refine the developmental picture; 3) map regional brain development using a more dense array (128 EEG electrodes) to measure EEG frequency and coherence and relate these measures to affect processing and regulation at different ages and across time, 4) for the first time, examine temporally refined measures of brain activity [e.g., event-related brain responses (ERPs)] in response to other sensory stimuli (e.g.,facial displays of emotions) across development, and 5) measure the source of child EEG signals by using the dense EEG array.

情绪的评价、调节和表达在人类行为的动机和沟通方面起着重要作用，对人类的最佳发展至关重要。 精神障碍诊断和统计手册（DSM-IV，美国精神病学协会，1994，例如，抑郁症、焦虑症、品行障碍）将无法调节负面情绪列为诊断标准。 然而，我们对儿童情感处理和调节的发展知之甚少。了解儿童如何调节情绪的第一步是了解他们如何处理情绪。我的NSERC资助的研究项目的主要目标是检查在生命的前四年中典型发育儿童的情感处理和调节的发展。 在最近NSERC资助的一系列研究中，我们发现了人类婴儿和成人在处理不同类型的情感听觉和视觉刺激时额叶和自主神经活动的不同模式。 拟议的NSERC资助期将使我们能够继续并扩展我们的工作，研究年龄较大的儿童和年轻人在典型人类发展中的情感处理和调节的发展。 我们将：1）在我们的初步研究中，招募年轻成年人的单独队列，以完善我们的措施，并将我们以前的发展工作扩展到成年人，2）招募儿童早期发展时间点的横断面队列，并招募24个月大的儿童的单独队列进行纵向跟踪，并在与横断面队列相同的时间点进行测试，以完善发展情况; 3）使用更密集的阵列（128个EEG电极）绘制局部大脑发育图，以测量EEG频率和相干性，并将这些测量与影响不同年龄和不同时间的处理和调节联系起来，4）首次检查大脑活动的时间细化测量[例如，事件相关脑反应（ERP）]响应于其他感觉刺激（例如，情绪的面部显示），以及5）通过使用密集EEG阵列来测量儿童EEG信号的来源。