Longitudinal study of emotion processing and regulation: An electrocortical approach

情绪处理和调节的纵向研究：电皮层方法

• 批准号: RGPIN-2017-05342
• 负责人: Schmidt, Louis
• 金额: $ 1.82万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=680854
• 关键词: Longitudinal; study; emotion; processing; regulation

Individual differences in childhood emotion regulation predict important developmental outcomes, such as later academic performance, social competence, socioeconomic status, as well as physical and mental health. Emotion regulation relies on the development of executive function (EF) the deliberate, top-down neurocognitive processes involved in emotion regulation. It is particularly related to “hot” aspects of EF, or the control processes that operate in emotionally significant situations. A first step in understanding how children regulate their emotions is to understand how they process them. Given the important outcomes of the development of emotion regulation, I propose to examine whether patterns of emotion processing in 6- to 14-year-old children are linked to emotion regulation. This age period is not only marked by important changes in emotion regulation, but also it has received relatively little attention for understanding how emotions develop and are processed in the brain.****** In a series of NSERC funded studies with infants and adults, we have found distinct patterns of frontal lobe, limbic, autonomic, and endocrine activity during the processing of fear, anger, and happiness in infants and adults, using behavioural, fMRI, electrocortical, autonomic, and endocrine measures (see Miskovic Schmidt & Miskovic, 2014). We have found that the experience of positive emotions (e.g., happiness) is associated with greater relative left frontal brain activity, whereas the experience of negative affect (e.g., fear) is associated with greater relative right frontal brain activity. ****** The proposed research will extend my prior NSERC work with infants and young adults to examine the development of emotion processing in typically-developing school age children and adolescents. Here, we will recruit cross-sectional cohorts of typically developing children at ages 6, 10 and 14 years. The youngest cohort will be followed longitudinally at the same time points. We will address the following questions: (1) Are there distinct patterns of electrocortical activity, heart rate, and cortisol responses during the processing of positive and negative emotions in school age children and adolescents, and do these patterns change with age? (2) Are individual differences in electrocortical activity related to emotion regulation? (3) For the first time, what are the oscillatory dynamics (measured with electroencephalogram [EEG]) that are associated with emotion processing and regulation in school age children and adolescents? ****** Emotion processing and regulation problems in childhood are economically costly to all Canadians in terms of mental health costs, work loss, and delinquency - let alone the toll they take on families and children who are affected. This proposal has implications for understanding basic brain and behavioural mechanisms underlying emotion regulatory problems.

童年情绪调节的个体差异预测了重要的发展结果，如以后的学习成绩、社会能力、社会经济地位以及身心健康。情绪调节依赖于执行功能（EF）的发展，这是一种涉及情绪调节的有意识的、自上而下的神经认知过程。它特别与EF的“热”方面有关，或者在情感上重要的情况下运作的控制过程。了解儿童如何调节情绪的第一步是了解他们如何处理情绪。鉴于情绪调节发展的重要成果，我建议研究6- 14岁儿童的情绪处理模式是否与情绪调节有关。这一时期不仅以情绪调节的重要变化为标志，而且在理解情绪如何在大脑中发展和处理方面也受到相对较少的关注。******在NSERC资助的一系列针对婴儿和成人的研究中，我们发现在婴儿和成人处理恐惧、愤怒和快乐的过程中，额叶、边缘、自主神经和内分泌活动的不同模式，使用行为、功能磁共振成像、电皮层、自主神经和内分泌测量（见Miskovic Schmidt & Miskovic， 2014）。我们发现，积极情绪（如快乐）的体验与相对较大的左额叶脑活动有关，而消极情绪（如恐惧）的体验与相对较大的右额叶脑活动有关。******拟议的研究将扩展我之前在NSERC对婴儿和年轻人的研究，以检查典型发展的学龄儿童和青少年的情绪处理发展。在这里，我们将招募6岁、10岁和14岁的典型发育儿童的横断面队列。将在同一时间点纵向跟踪最年轻的队列。我们将解决以下问题：(1)学龄儿童和青少年在处理积极和消极情绪时是否存在不同的皮层电活动、心率和皮质醇反应模式，这些模式是否随着年龄的增长而改变？(2)皮层电活动的个体差异是否与情绪调节有关？(3)第一次，在学龄儿童和青少年中，与情绪加工和调节相关的振荡动力学（用脑电图测量）是什么？******童年时期的情绪处理和调节问题对所有加拿大人来说都是经济上昂贵的，包括心理健康成本、失业和犯罪，更不用说对受影响的家庭和儿童造成的损失了。这一建议对理解情绪调节问题背后的基本大脑和行为机制具有启示意义。