Novel catalytic amination processes

该项目的全球科学目标是开发新的工具，利用一锅法和过渡金属催化过程精制重要的含氮分子。C-N键的生成是合成有机化学中的重要挑战之一，因为这些键存在于许多具有重要生物学性质的分子中。尽管以前报告了一些方法，但对现有技术的改进以及新方法的开发仍然是非常可取的。我们的目标不仅是开发更有效的合成策略，而且通过使用新的催化反应和新的多催化策略，向更绿色的过程收敛，大大减少所需试剂和溶剂的量，从而产生更少的废物和副产品。

The global scientific objective of this project is to develop new tools for the elaboration of important nitrogen-containing molecules, using one-pot and transition metal-catalyzed processes. The creation of C-N bonds is one of the important challenges in synthetic organic chemistry, as these bonds are found in many molecules possessing important biological properties. Although a number of methods have been previously reported, improvements of the existing technologies as well as developments of novel approaches are still highly desirable. Our goal is not only to develop more efficient synthetic strategies, but also to converge towards greener processes, by using new catalyzed-reactions, and new multicatalytic strategies, which considerably decrease the amount of required reagents and solvents, thus producing less waste and byproducts.