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Mechanisms underlying the trophic and chemotropic effects of retinoic acid

Mechanisms underlying the trophic and chemotropic effects of retinoic acid
视黄酸的营养和趋化作用的机制
批准号:
238373-2010
负责人:
Spencer, Gaynor
金额:
$4.66万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-01-01 至 2012-12-31

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英文摘要
My research program focusses on how nerve cells extend their processes during development and nerve regeneration and then form connections with appropriate partner cells. To this end, I use the large identifiable nerve cells of the adult mollusc, Lymnaea stagnalis, which can regenerate in cell culture. At the growing ends of regenerating neurites, structures known as growth cones are found. These structures are responsible for pathfinding during nervous system development and regeneration, and then selecting and forming appropriate connections with target cells.
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Understanding how retinoic acid affects neurite outgrowth and synaptic function using invertebrate neurons.
  • 批准号:
    RGPIN-2021-02825
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.64万
  • 财政年份:
    2022
  • 负责人:
    Spencer, Gaynor
  • 依托单位:
Understanding how retinoic acid affects neurite outgrowth and synaptic function using invertebrate neurons.
  • 批准号:
    RGPIN-2021-02825
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.64万
  • 财政年份:
    2021
  • 负责人:
    Spencer, Gaynor
  • 依托单位:
Essential upgrade to a cell culture imaging and recording rig to study the role of retinoids (Vitamin A metabolites) in nervous system function
  • 批准号:
    RTI-2022-00225
  • 项目类别:
    Research Tools and Instruments
  • 资助金额:
    $7.83万
  • 财政年份:
    2021
  • 负责人:
    Spencer, Gaynor
  • 依托单位:
Mechanisms underlying the effects of retinoic acid on neurite outgrowth and network plasticity
  • 批准号:
    RGPIN-2015-03780
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.28万
  • 财政年份:
    2020
  • 负责人:
    Spencer, Gaynor
  • 依托单位:
海外基金