Removal mechanisms, nature and relative toxicity of transformation products of pharmaceuticals in advanced wastewater treatment

废水深度处理中药物转化产物的去除机理、性质和相对毒性

• 批准号: 312545-2010
• 负责人: Yargeau, Viviane
• 金额: $ 1.46万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=481325
• 关键词: Removal; mechanisms; nature; relative; toxicity

Hundreds of compounds including pharmaceuticals and endocrine disruptors have been identified in wastewaters in concentrations in the ug/L range while being detected in the ng/L range in surface waters. Traces of some of these compounds have also been detected in drinking water. Little information is available on the fate of these contaminants in the environment and in engineered systems but previous studies showed that conventional wastewater treatment approaches are not efficient at removing most of these compounds. Previous research conducted in my group showed that ozonation used as a tertiary treatment significantly enhance the removal of several of these compounds in municipal or industrial wastewaters. However, many questions remain: What is the nature of the transformation products? What are the most efficient oxidative approaches for the treatment of industrial wastewaters? What are the risks associated with the release of these transformation products in the environment? The long term objectives of the proposed research, supported by a state-of-the-art infrastructure obtained with the support of two grants awarded by the Canada Foundation for Innovation (Leaders Opportunity and New Initiatives Funds) are: 1) To improve our knowledge of the factors affecting the biodegradability of pharmaceuticals in the environment, 2) To assessing the efficiency and impact of ozonation of municipal wastewater on the fate of pharmaceuticals as well as the residual toxicity of the treated water and 3) To study other oxidative treatment approaches for the treatment of wastewaters from the pharmaceuticals industry in order to prioritize actions, established sound regulations and develop strategies to protect the environment and public health. The methodology proposed will result in the training of graduate students; will strengthen collaboration developed with toxicologists as well as with the pharmaceutical industry and wastewater treatment plants in Quebec. A better understanding and control of the removal mechanisms of these compounds will mitigate the risks associated with their presence in the environment.

在沃茨中发现了浓度在微克/升范围内的数百种化合物，包括药物和内分泌干扰物，而在地表沃茨中检测到的浓度在纳克/升范围内。在饮用水中也发现了这些化合物的痕迹。关于这些污染物在环境和工程系统中的命运的信息很少，但以前的研究表明，传统的废水处理方法不能有效地去除大多数这些化合物。我的小组以前进行的研究表明，臭氧化作为三级处理显着提高城市或工业废水中这些化合物的去除。然而，许多问题仍然存在：转型产品的性质是什么？处理工业废水最有效的氧化方法是什么？在环境中发布这些转换产品有哪些风险？ 拟议研究的长期目标，由加拿大创新基金会授予的两笔赠款支持的最先进的基础设施提供支持（领导者机会和新倡议基金）是：1）提高我们对影响药物在环境中生物降解性的因素的认识，2）评估城市废水臭氧化的效率和对药物命运的影响以及处理后水的残留毒性; 3）研究制药行业废水处理的其他氧化处理方法，以便确定行动优先顺序、建立健全的法规并制定保护环境和公众健康的战略。拟议的方法将导致研究生的培训;将加强与毒理学家以及与魁北克的制药业和废水处理厂的合作。 更好地了解和控制这些化合物的去除机制将减轻与其在环境中存在相关的风险。