New periodic mesoporous organic silicas for catalysis

用于催化的新型周期性介孔有机二氧化硅

• 批准号: 355546-2010
• 负责人: MacQuarrie, Stephanie
• 金额: $ 2.33万
• 依托单位: Cape Breton University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=482744
• 关键词: New; periodic; mesoporous; organic; silicas

The MacQuarrie research program combines two unique fields of chemistry, nanomaterials and catalysis by synthesizing and characterizing highly organized functionalized nanomaterials composed of proline and N-heterocyclic carbene-derived skeletons. The resulting immobilized organocatalysts will be invesitgated in C-C bond forming reactions such as the aldol or Stetter reaction to test the applicability and reusability of the catalysts and discover optimum reaction conditions. These highly ordered organosilicas will have uniform porosity, permitting reactants to freely access the catalytically active microenvironments leading to highly effective enantioselection. The novel organic siloxane monomers will be prepared through a simple modular synthetic approach and directly incorporated into three-dimensional inert, thermally stable and non-toxic silicon oxide backbone through six covalent bonds, leading to complete homogeneous distribution of the organic components with strong anchoring points.

麦夸里的研究项目通过合成和表征由脯氨酸和 N-杂环卡宾衍生骨架组成的高度组织化的功能化纳米材料，结合了化学、纳米材料和催化两个独特的领域。 所得的固定化有机催化剂将在C-C键形成反应（例如羟醛反应或Stetter反应）中进行研究，以测试催化剂的适用性和可重复使用性，并发现最佳反应条件。这些高度有序的有机二氧化硅将具有均匀的孔隙率，允许反应物自由进入催化活性微环境，从而实现高效的对映选择。新型有机硅氧烷单体将通过简单的模块化合成方法制备，并通过六个共价键直接掺入三维惰性、热稳定且无毒的氧化硅主链中，从而使有机组分完全均匀分布，具有强锚定点。