Identification of Matriptase-2 natural substrates & cleavage specificity in Anemia by Proteomics Approach

Matriptase-2 天然底物的鉴定

• 批准号: 173587
• 负责人: Barr Olivier
• 金额: $ 6.56万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-10-01 至 2010-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=173587&lang=en
• 关键词: Anemia; Degradomics; Iron Homeostasis; Knock-Out Mouse; Proteomics

Iron is an essential nutrient for all living organisms: it is necessary for oxygen transport using the carrier protein hemoglobin and in metabolic reactions. Iron deficiency can lead to several severe pathologies such as anemia, while in excess it is toxi

铁是所有生物体的必需营养素：它是使用载体蛋白血红蛋白和代谢反应进行氧气运输所必需的。缺铁可导致几种严重的病理，如贫血，而过量则是毒性。