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Control of beta-cell mitochondrial physiology by core anti-apoptosis proteins

Control of beta-cell mitochondrial physiology by core anti-apoptosis proteins
通过核心抗凋亡蛋白控制 β 细胞线粒体生理学
批准号：
238948
负责人：
Luciani Dan S
金额：
$25.6万
依托单位：
BC Children's Hospital Research Institute
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2011
资助国家：
加拿大
项目状态：
已结题
起止时间：
2011-09-01 至 2014-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=238948&lang=en
关键词：
Apoptosis Diabetes In Vivo Glucose Homeostasis Islet Biology Knockout Mouse Models Live Cell Microscopy Metabolic Stress Mitochondrial Physiology

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Along with the rise in obese Canadians, there is an alarming increase in the number of Canadians with glucose intolerance and diabetes. In healthy individuals, a rise in blood sugar (glucose) stimulates insulin release from beta-cells in the pancreas. Thi
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The interplay of apoptosis proteins, mitochondria and premature senescence in beta-cell fate and diabetes
Control of beta-cell mitochondrial physiology and adaptation by core anti-apoptosis proteins
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