Control of Microtubule Architecture by Doublecortin

Doublecortin 对微管结构的控制

• 批准号: 241135
• 负责人: Brouhard Gary J
• 金额: $ 21.86万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Salary Programs
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-09-01 至 2016-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=241135&lang=en
• 关键词: Biophysics; Cortex; Doublecortin; Lissencephaly; Microtubulue; Neuron; Nucleation; Single Molecule

The outermost layer of the brain, just below the skull, is the cerebral cortex. The cerebral cortex is the seat of our intellect, and in healthy people it has many deep folds. In unfortunate cases, however, a genetic mutation causes a loss of these folds,

大脑的最外层，就在头骨下面，是大脑皮层。大脑皮层是我们智力的所在地，在健康的人身上，它有许多很深的褶皱。然而，在不幸的情况下，基因突变会导致这些折叠的丢失，