An Inverse Gas Chromatographic System for the Charaterization of Biopolymers

用于表征生物聚合物的反相气相色谱系统

• 批准号: 423083-2012
• 负责人: Choi, Phillip
• 金额: $ 4.59万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=495888
• 关键词: Inverse; Gas; Chromatographic; System; Charaterization

In this proposal, funds for an inverse gas chromatographic (IGC) system with the associated accessories (e.g., computer hardware and software for data collection and analysis, a roto-evaporator for the preparation of IGC coulmns) are requested. IGC is a simple yet versatile technique that can be used to study miscibility of polymer solutions and blends, surface characteristics of inorganic solids and diffusivity of small molecules in polymers. The proposed IGC system will be used for the study of diffusivity of both inorganic and organic compounds (e.g., oxygen, water and low molecular weight organic solvents) in biopolymers such as acetoxypropyl xylan (APX) and block copolymers used in drug delivery systems. Here, APX is chemically modified wood product that can form smooth films. The preliminary results indicate that APX has a high potential to be used in many packaging applications. Therefore, its barrier properties need to be determined. And the proposed IGC system will be used for such a purpose.

在本提案中，为带有相关附件（例如，需要用于数据收集和分析的计算机硬件和软件、用于制备IGC样品的旋转蒸发器。 IGC是一种简单而通用的技术，可用于研究聚合物溶液和共混物的溶解性，无机固体的表面特性和小分子在聚合物中的扩散性。 拟议的IGC系统将用于研究无机和有机化合物的扩散率（例如，氧、水和低分子量有机溶剂）在生物聚合物如乙酰氧基丙基木聚糖（APX）和药物递送系统中使用的嵌段共聚物中。 在这里，APX是一种化学改性的木材产品，可以形成光滑的薄膜。 初步结果表明，APX在许多包装应用中具有很高的潜力。 因此，需要确定其阻隔性能。 建议的IGC系统将用于此目的。