An Inverse Gas Chromatographic System for the Charaterization of Biopolymers

在这项提案中，需要为反相色谱系统及其相关附件(例如，用于数据收集和分析的计算机硬件和软件、用于制备反相色谱系统的旋转蒸发器)申请资金。IGC是一种简单而通用的技术，可用于研究聚合物溶液和共混物的相容性、无机固体的表面特征和小分子在聚合物中的扩散系数。建议的IGC系统将用于研究无机和有机化合物(如氧、水和低分子有机溶剂)在生物聚合物中的扩散系数，如用于药物输送系统的乙酰丙基木聚糖(APX)和嵌段共聚物。在这里，APX是经过化学修饰的木制品，可以形成光滑的薄膜。初步结果表明，APX在许多包装领域具有很高的应用潜力。因此，需要确定其阻隔性能。拟议的政府间气相会议系统将用于这一目的。

In this proposal, funds for an inverse gas chromatographic (IGC) system with the associated accessories (e.g., computer hardware and software for data collection and analysis, a roto-evaporator for the preparation of IGC coulmns) are requested. IGC is a simple yet versatile technique that can be used to study miscibility of polymer solutions and blends, surface characteristics of inorganic solids and diffusivity of small molecules in polymers. The proposed IGC system will be used for the study of diffusivity of both inorganic and organic compounds (e.g., oxygen, water and low molecular weight organic solvents) in biopolymers such as acetoxypropyl xylan (APX) and block copolymers used in drug delivery systems. Here, APX is chemically modified wood product that can form smooth films. The preliminary results indicate that APX has a high potential to be used in many packaging applications. Therefore, its barrier properties need to be determined. And the proposed IGC system will be used for such a purpose.