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Two dimensional gas chromatographic analysis of alkylated polycyclic aromatic hydrocarbons

烷基化多环芳烃的二维气相色谱分析

基本信息

批准号：
512239-2017
负责人：
Tomy, Gregg
金额：
$ 1.82万
依托单位：
University of Manitoba
依托单位国家：
加拿大
项目类别：
Engage Grants Program
财政年份：
2017
资助国家：
加拿大
起止时间：
2017-01-01 至 2018-12-31
项目状态：
已结题

来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=640644
关键词：
Two dimensional gas chromatographic analysis

项目摘要

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous in nature with vast structural diversity; consisting of two or more aromatic rings in their structures, having different source materials; biogenic, petrogenic or pyrogenic. Numerous studies have confirmed their carcinogenicity, toxicity, mutagenicity and persistence in the environment. Alkyl-PAHs (APAHs) which are known PAHs substituted with a methyl, ethyl or other alkyl group at different positions have been reported to be more toxic and available at concentrations higher than their parent PAHs. The current approach to measuring these compounds in environmental samples rely on one-dimensional gas chromatography. However, because of the inherent complexity of APAHs, this approach is unable to effectively resolve the large number of isomers that are theoretically possible. Maxxam Analytics has been leading contaminants analysis and novel method development for industry, governments and academia for four decades. As leaders in hydrocarbon analyses, Maxxam has developed advanced methods to support petroleum sector monitoring initiatives, hydrocarbon analysis for expanded suites of PAH targets and forensic 'fingerprinting' studies. Maxxam has identified an urgent need to develop a more accurate approach for quantitation of APAHs as this will aide in meaningful source apportionment indicators that has been a primary focus of the oil sands monitoring programs. Here we propose closely with Maxxam Analytics to develop a more accurate and a reliable quantitation methodology that is based on two dimensional gas chromatography.

多环芳烃（PAHs）在自然界中普遍存在，结构多样，由两个或两个以上的芳香环组成，具有不同的来源，有生物成因的、岩石成因的或热解成因的。许多研究已证实其致癌性、毒性、致突变性和在环境中的持久性。烷基多环芳烃（APAHs）是已知的在不同位置被甲基、乙基或其他烷基取代的多环芳烃，据报道其毒性更大，并且可在高于其母体多环芳烃的浓度下获得。目前测量环境样品中这些化合物的方法依赖于一维气相色谱法。然而，由于APAH固有的复杂性，这种方法无法有效地解决理论上可能存在的大量异构体。Maxxam Analytics四十年来一直为工业、政府和学术界领导污染物分析和新方法开发。作为碳氢化合物分析的领导者，Maxxam开发了先进的方法来支持石油部门的监测计划，碳氢化合物分析扩展套PAH目标和法医“指纹”研究。Maxxam已确定迫切需要开发一种更准确的APAH定量方法，因为这将有助于制定有意义的源解析指标，而源解析指标一直是油砂监测计划的主要焦点。在这里，我们建议与Maxxam Analytics密切合作，开发一种基于二维气相色谱的更准确和可靠的定量方法。