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Identifying novel roles of calcineurin signaling in the control of multiple complementary pathways affecting the dystrophic phenotype

Identifying novel roles of calcineurin signaling in the control of multiple complementary pathways affecting the dystrophic phenotype
确定钙调神经磷酸酶信号在控制影响营养不良表型的多种互补途径中的新作用
批准号：
259201
负责人：
Michel Robin N
金额：
$10.27万
依托单位：
Concordia University (Montreal, Quebec)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-03-01 至 2015-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=259201&lang=en
关键词：
Calcineurin Modulators Cell Biology Intracellular Calcium Modulators Intracellular Signaling Muscular Dystrophy Plasmid Transfections Post-Transcriptional Qrt-Pcr Transgenic Mice Utrophin Expression

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中文摘要
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英文摘要
One of the most promising therapeutic strategies for countering muscular dystrophy is to replace the missing muscle dystrophin protein that is a signature of this disease with its protein "twin sister" utrophin, which is present in small amounts in the mu
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Role of calcineurin and its signaling modulators in the dystrophic phenotype
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