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Mechanisms of Aspergillus induced chronic airway disease

Mechanisms of Aspergillus induced chronic airway disease
曲霉菌诱发慢性气道疾病的机制
批准号:
252045
负责人:
Sheppard Donald C
金额:
$39.01万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-03-01 至 2017-03-01

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中文摘要
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英文摘要
The mold Aspergillus fumigatus colonizes the lungs of up to half of patients with cystic fibrosis, whose lung function then worsens. Antifungal therapy is rarely successful in eradicating the fungus, suggesting a need for new therapies for this condition.
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Development of immunotherapeutics against Aspergillus fumigatus
Identification and characterization of a novel polysaccharide virulence factor of Aspergillus fumigatus
Human Fungal Infections - Targeting host-pathogen interactions to develop novel antifungal therapies
Recombinant hydrolases as anti-biofilm therapies for Aspergillus infections
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