Design of Lipid Nanoparticle Systems for the Systemic Delivery of siRNA
Design of Lipid Nanoparticle Systems for the Systemic Delivery of siRNA
批准号:
252536
负责人:
Cullis Pieter R
金额:
$51.0万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-03-01 至 2017-03-01
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Small interfering RNA (siRNA) oligonucleotides can efficiently and specifically "silence" the production of particular "target" proteins in cells by binding to the mRNA that codes for that protein. This results in a catalytic destruction of the targeted m
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Rational Design of Lipid Nanoparticle Systems for mRNA Delivery
-
批准号:478978
-
项目类别:Operating Grants
-
资助金额:$78.86万
-
财政年份:2023
-
负责人:Cullis Pieter R
-
依托单位:
Newly Optimized LNP Systems for Genetic drugs and Gene therapy in Neurological diseases
-
批准号:469979
-
项目类别:Operating Grants
-
资助金额:$77.03万
-
财政年份:2022
-
负责人:Cullis Pieter R
-
依托单位:
Development of LNP/mRNA systems for direct transfection and generation of functional Chimeric Antigen Receptor (CAR) T-cells in-vivo for treatment of blood and other cancer cell types
-
批准号:463373
-
项目类别:Operating Grants
-
资助金额:$62.42万
-
财政年份:2022
-
负责人:Cullis Pieter R
-
依托单位:
Liver as a bioreactor for robust production of SARS-CoV-2 neutralizing antibodies
-
批准号:429662
-
项目类别:Operating Grants
-
资助金额:$17.3万
-
财政年份:2020
-
负责人:Cullis Pieter R
-
依托单位:
Lipid nanomedicines for health and disease
-
批准号:334137
-
项目类别:Operating Grants
-
资助金额:$154.56万
-
财政年份:2015
-
负责人:Cullis Pieter R
-
依托单位:
Liposomal nanoparticle formulations of difficult to formulate drugs
-
批准号:210579
-
项目类别:Operating Grants
-
资助金额:$31.35万
-
财政年份:2010
-
负责人:Cullis Pieter R
-
依托单位:
Personalized siRNA-Based Nanomedicines
-
批准号:209211
-
项目类别:Operating Grants
-
资助金额:$178.31万
-
财政年份:2010
-
负责人:Cullis Pieter R
-
依托单位:
Personalized siRNA-Based Nanomedicines
-
批准号:196888
-
项目类别:Operating Grants
-
资助金额:$0.0万
-
财政年份:2009
-
负责人:Cullis Pieter R
-
依托单位:
Investigations of nanoparticulate formulations of lipophilic prodrugs
-
批准号:183810
-
项目类别:Operating Grants
-
资助金额:$7.29万
-
财政年份:2008
-
负责人:Cullis Pieter R
-
依托单位:
海外基金