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Misfolding of Cu/Zn superoxide dismutase by pathological FUS and TDP43: relevance to amyotrophic lateral sclerosis

Misfolding of Cu/Zn superoxide dismutase by pathological FUS and TDP43: relevance to amyotrophic lateral sclerosis
病理性 FUS 和 TDP43 引起的 Cu/Zn 超氧化物歧化酶错误折叠:与肌萎缩侧索硬化症的相关性
批准号:
259206
负责人:
Cashman Neil R
金额:
$6.53万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-03-01 至 2015-03-01

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中文摘要
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英文摘要
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is an incurable neuromuscular disease characterized by progressive paralysis of the muscles of the limbs, speech, swallowing, and respiration due to the progressive degeneration of m
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A Defined Abeta Oligomer Epitope: Theranostic Applications
Pathobiological mechanisms of misfolded wild-type Cu/Zn superoxide dismutase: A common pathway in amyotrophic lateral sclerosis
A defined cyclic peptide epitope specific to Abeta oligomers: Active and passive vaccination in mouse models of Alzheimer's disease
  • 批准号:
    268560
  • 项目类别:
    Operating Grants
  • 资助金额:
    $21.86万
  • 财政年份:
    2012
  • 负责人:
    Cashman Neil R
  • 依托单位:
CANADA RESEARCH CHAIRHOLDER - TITULAIRE DE CHAIRE DE RECHER DU CANADA
  • 批准号:
    256542
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2011
  • 负责人:
    Cashman Neil R
  • 依托单位:
海外基金