Impact of genetic polymorphism and folate intake on methyl group utilization in brain
Impact of genetic polymorphism and folate intake on methyl group utilization in brain
批准号:
184532
负责人:
Jadavji Nafisa M
金额:
$7.65万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-10-01 至 2011-10-01
中文摘要
叶酸是影响DNA完整性、甲基化反应和基因表达的重要维生素。大脑对这些过程中的干扰特别敏感。参与叶酸代谢的关键酶的遗传缺陷,如me
英文摘要
Folates are important vitamins that affect DNA integrity, methylation reactions and gene expression. The brain is particularly sensitive to disturbances in these processes. Genetic deficiencies of critical enzymes involved in folate metabolism, such as me
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会议论文
MTHFR deficiency increases vulnerability and impairment in an aged mouse model of stroke
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批准号:364536
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项目类别:
-
资助金额:$0.07万
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财政年份:2017
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负责人:Jadavji Nafisa M
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依托单位:
海外基金