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Stress regulation of heart fibrosis through integrin-mediated activation of TGF-beta

Stress regulation of heart fibrosis through integrin-mediated activation of TGF-beta
通过整合素介导的 TGF-β 激活对心脏纤维化的应激调节
批准号:
266793
负责人:
Hinz Boris
金额:
$47.06万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2017-09-01

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中文摘要
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英文摘要
Fibrosis is a major cause for heart failure and death with no effective therapies available to date. When an infarct destroys parts of the heart muscle, connective tissue fibroblasts are activated into myofibroblasts (MFs) to repair the damage. They start
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会议论文
Mechanical Imprinting of Epigenetic Memory in Therapeutic Mesenchymal Stromal Cells
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    478875
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    Operating Grants
  • 资助金额:
    $54.06万
  • 财政年份:
    2023
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Mechanical mechanisms of inflammatory cell attraction to myofibroblasts in collagen matrix - implications for lung fibrosis
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    357572
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    $52.39万
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    2016
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Innovative biomechanical and molecular strategies to fight fibrosis
  • 批准号:
    355470
  • 项目类别:
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  • 资助金额:
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  • 财政年份:
    2016
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Repurposing biomolecules for the treatment of epidermolysis bullosa
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    311443
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  • 财政年份:
    2014
  • 负责人:
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  • 依托单位:
海外基金