Assembly and disassembly of cucumber necrosis virus and role of host components

植物病毒是造成世界范围内多种作物经济损失的罪魁祸首。一些减少病毒对作物生产影响的措施已经到位，然而，植物病毒已被证明难以控制。我实验室的研究旨在了解植物病毒繁殖周期的具体方面，以及病毒在这些过程中使用的宿主成分的性质。为此，我们提出分析植物病毒颗粒在植物细胞中如何分解，以及新合成的成分如何重新组装形成新的病毒颗粒。此外，还建议研究病毒与哪些宿主成分相互作用以进行组装和拆卸。植物病毒的分解对于建立感染至关重要，而新颗粒的组装使病毒能够在整个植物和植物之间传播。了解病毒感染周期的这些基本方面将有助于制定控制病毒感染的新策略。

Plant viruses are responsible for economic loss in a variety of crops worldwide. Several measures to reduce the impact of viruses on crop production are in place, however, plant viruses have proven difficult to control. Research in my laboratory aims to understand specific aspects of the multiplication cycle of a plant virus, and the nature of host components that the virus uses for these processes. Toward this aim, it is proposed to analyze how a plant virus particle disassembles in a plant cell and how the newly synthesized components reassemble to form new virus particles. In addition, it is proposed to investigate which host components the virus interacts with in order to assemble and disassemble. Disassembly of a plant virus is essential for the establishment of infection and assembly of new particles allows the virus to spread throughout and between plants. Understanding these essential aspects of the virus infection cycle will contribute to the development of new strategies for controlling virus infection.