Mutagenomics - Bridging Chemistry and Biology
Mutagenomics - Bridging Chemistry and Biology
批准号:
155155-2013
负责人:
Loppnow, Glen
金额:
$2.48万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-01-01 至 2014-12-31
中文摘要
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英文摘要
A major goal of our research program is to measure and understand the molecular-level damage mechanisms in nucleic acids. Our approach combines the development of novel tools and massively-parallel platforms for measuring molecular-scale nucleic acid damage, with elucidation of reaction mechanisms. We use primarily fluorescence, absorption and resonance Raman to characterize nucleic acid damage in detail, starting with the femtosecond excited-state structural dynamics. Our primary research interests include probing the deleterious effects of various damage insults on DNA and RNA on a genome-wide scale and understanding the sequence and structural determinants of such damage.
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会议论文
Fundamental Molecular Mechanisms of DNA Damage
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批准号:RGPIN-2015-06247
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.04万
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财政年份:2019
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负责人:Loppnow, Glen
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依托单位:
Fundamental Molecular Mechanisms of DNA Damage
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批准号:RGPIN-2015-06247
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.04万
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财政年份:2018
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负责人:Loppnow, Glen
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依托单位:
Fundamental Molecular Mechanisms of DNA Damage
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批准号:RGPIN-2015-06247
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.04万
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财政年份:2017
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负责人:Loppnow, Glen
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依托单位:
Fundamental Molecular Mechanisms of DNA Damage
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批准号:RGPIN-2015-06247
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.04万
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财政年份:2016
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负责人:Loppnow, Glen
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依托单位:
Fundamental Molecular Mechanisms of DNA Damage
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批准号:RGPIN-2015-06247
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.04万
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财政年份:2015
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负责人:Loppnow, Glen
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依托单位:
Nucleic acid excited-state structure and dynamics: fundamentals to applications
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批准号:155155-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.72万
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财政年份:2012
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负责人:Loppnow, Glen
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依托单位:
Nucleic acid excited-state structure and dynamics: fundamentals to applications
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批准号:155155-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.72万
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财政年份:2011
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负责人:Loppnow, Glen
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依托单位:
Nucleic acid excited-state structure and dynamics: fundamentals to applications
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批准号:155155-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.72万
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财政年份:2010
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负责人:Loppnow, Glen
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依托单位:
Nucleic acid excited-state structure and dynamics: fundamentals to applications
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批准号:155155-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.72万
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财政年份:2009
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负责人:Loppnow, Glen
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依托单位:
Nucleic acid excited-state structure and dynamics: fundamentals to applications
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批准号:155155-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.72万
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财政年份:2008
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负责人:Loppnow, Glen
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依托单位:
Femtosecond blue laser for genomics
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批准号:359122-2008
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项目类别:Research Tools and Instruments - Category 1 (<$150,000)
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资助金额:$4.64万
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财政年份:2007
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负责人:Loppnow, Glen
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依托单位:
Excited-state dynamics of biological systems from resonance reman spectroscopy
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批准号:155155-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.59万
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财政年份:2007
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负责人:Loppnow, Glen
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依托单位:
Excited-state dynamics of biological systems from resonance reman spectroscopy
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批准号:155155-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.59万
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财政年份:2006
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负责人:Loppnow, Glen
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依托单位:
Excited-state dynamics of biological systems from resonance reman spectroscopy
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批准号:155155-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.59万
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财政年份:2005
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负责人:Loppnow, Glen
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依托单位:
Excited-state dynamics of biological systems from resonance reman spectroscopy
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批准号:155155-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.59万
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财政年份:2004
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负责人:Loppnow, Glen
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依托单位:
Excited-state dynamics of biological systems from resonance reman spectroscopy
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批准号:155155-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.59万
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财政年份:2003
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负责人:Loppnow, Glen
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依托单位:
Raman spectroscopy for the oil industry
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批准号:223820-1999
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项目类别:Collaborative Research and Development Grants
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资助金额:$3.3万
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财政年份:2002
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负责人:Loppnow, Glen
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依托单位:
Resonance raman structural probes of excited-state dynamics in structured environments
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批准号:155155-1999
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.44万
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财政年份:2002
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负责人:Loppnow, Glen
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依托单位:
Resonance raman structural probes of excited-state dynamics in structured environments
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批准号:155155-1999
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.44万
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财政年份:2001
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负责人:Loppnow, Glen
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依托单位:
Raman spectroscopy for the oil industry
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批准号:223820-1999
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项目类别:Collaborative Research and Development Grants
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资助金额:$3.72万
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财政年份:2001
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负责人:Loppnow, Glen
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依托单位:
海外基金