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A Functional Nuclear Pyruvate Dehydrogenase Complex is Important for a Mitochondria-Independent Generation of Acetyl-CoA and Histone Acetylation in the Nucleus

A Functional Nuclear Pyruvate Dehydrogenase Complex is Important for a Mitochondria-Independent Generation of Acetyl-CoA and Histone Acetylation in the Nucleus
功能性核丙酮酸脱氢酶复合物对于细胞核中乙酰辅酶A和组蛋白乙酰化的线粒体独立生成非常重要
批准号:
267111
负责人:
Michelakis Evangelos D
金额:
$59.28万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2017-09-01

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中文摘要
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英文摘要
The regulation of genetic information in the cell depends on the function of the energy factories of the cell, the mitochondria. This way energy availability can be coordinated with the growth of the cell, which is regulated by the nucleus. However, there
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Canada Research Chair - Tier 1 - CIHR Funded
  • 批准号:
    384876
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2017
  • 负责人:
    Michelakis Evangelos D
  • 依托单位:
Mitochondrial targeting as a novel therapeutic approach to human disease: a translational program
  • 批准号:
    333909
  • 项目类别:
    Operating Grants
  • 资助金额:
    $281.39万
  • 财政年份:
    2015
  • 负责人:
    Michelakis Evangelos D
  • 依托单位:
Mitochondrial suppression in pulmonary hypertension
  • 批准号:
    266953
  • 项目类别:
    Operating Grants
  • 资助金额:
    $59.27万
  • 财政年份:
    2012
  • 负责人:
    Michelakis Evangelos D
  • 依托单位:
The Metabolic basis of Cancer Angiogenesis
  • 批准号:
    248584
  • 项目类别:
    Operating Grants
  • 资助金额:
    $0.0万
  • 财政年份:
    2011
  • 负责人:
    Michelakis Evangelos D
  • 依托单位:
海外基金