A Functional Nuclear Pyruvate Dehydrogenase Complex is Important for a Mitochondria-Independent Generation of Acetyl-CoA and Histone Acetylation in the Nucleus
A Functional Nuclear Pyruvate Dehydrogenase Complex is Important for a Mitochondria-Independent Generation of Acetyl-CoA and Histone Acetylation in the Nucleus
批准号:
267111
负责人:
Michelakis Evangelos D
金额:
$59.28万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-09-01 至 2017-09-01
中文摘要
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英文摘要
The regulation of genetic information in the cell depends on the function of the energy factories of the cell, the mitochondria. This way energy availability can be coordinated with the growth of the cell, which is regulated by the nucleus. However, there
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Canada Research Chair - Tier 1 - CIHR Funded
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批准号:384876
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项目类别:
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资助金额:$101.99万
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财政年份:2017
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负责人:Michelakis Evangelos D
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依托单位:
Mitochondrial targeting as a novel therapeutic approach to human disease: a translational program
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批准号:333909
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项目类别:Operating Grants
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资助金额:$281.39万
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财政年份:2015
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负责人:Michelakis Evangelos D
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依托单位:
Mitochondrial suppression in pulmonary hypertension
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批准号:266953
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项目类别:Operating Grants
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资助金额:$59.27万
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财政年份:2012
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负责人:Michelakis Evangelos D
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依托单位:
The Metabolic basis of Cancer Angiogenesis
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批准号:248584
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项目类别:Operating Grants
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资助金额:$0.0万
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财政年份:2011
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负责人:Michelakis Evangelos D
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依托单位:
Early phase clinical trials with the small molecule DCA in Pulmonary Arterial Hypertension
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批准号:239047
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项目类别:Operating Grants
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资助金额:$21.14万
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财政年份:2011
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负责人:Michelakis Evangelos D
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依托单位:
Nogo, the ER-mitochondria unit and the vascular remodeling of pulmonary hypertension
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批准号:225284
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项目类别:Operating Grants
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资助金额:$55.96万
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财政年份:2011
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负责人:Michelakis Evangelos D
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依托单位:
CRC tier 1
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批准号:241516
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项目类别:
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资助金额:$101.99万
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财政年份:2010
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负责人:Michelakis Evangelos D
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依托单位:
海外基金