Estrogen and cognitive strategy

雌激素和认知策略

• 批准号: 311886-2010
• 负责人: Brake, Wayne
• 金额: $ 1.97万
• 依托单位: Concordia University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=526292
• 关键词: Estrogen; cognitive; strategy

It has been known for some time that the female hormone, estrogen, plays a role in cognition in women and female animals. Yet, there is debate on whether estrogen improves learning and memory. We suggest that estrogen affects the way a task is approached, which can be beneficial or impairing for learning and memory - depending on the task. We have shown that estrogen affects a neurotransmitter in the brain called dopamine. Dopamine is important in learning and memory. What is not yet known, is how exactly estrogen affects dopamine in the brain or how this interaction affects cognition. The purpose of this research is to increase our understanding of how this female hormone affects dopamine systems in the brain and subsequent cognition.

一段时间以来，人们就知道雌性激素（雌激素）在女性和雌性动物的认知中发挥着重要作用。 然而，关于雌激素是否可以改善学习和记忆仍存在争议。我们认为雌激素会影响完成任务的方式，这可能有益或损害学习和记忆——具体取决于任务。我们已经证明雌激素会影响大脑中一种称为多巴胺的神经递质。 多巴胺对于学习和记忆很重要。目前尚不清楚雌激素究竟如何影响大脑中的多巴胺或这种相互作用如何影响认知。 这项研究的目的是加深我们对这种女性激素如何影响大脑中的多巴胺系统以及随后的认知的了解。