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HMG-CoA reductase in Alzheimer's Disease: Identification of a novel protective variant and unique polymorphisms that modulate Alzheimer pathophysiology.

HMG-CoA reductase in Alzheimer's Disease: Identification of a novel protective variant and unique polymorphisms that modulate Alzheimer pathophysiology.
阿尔茨海默氏病中的 HMG-CoA 还原酶：鉴定调节阿尔茨海默病病理生理学的新型保护性变体和独特的多态性。
批准号：
170522
负责人：
Poirier Judes
金额：
$48.96万
依托单位：
CIUSSS de l'Ouest-de-l'Ile-de-Montral-Douglas Hospital
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2008
资助国家：
加拿大
项目状态：
已结题
起止时间：
2008-09-01 至 2013-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=170522&lang=en
关键词：
Alzheimer'S Disease Cell Biology Cholesterol Genetics Lipid Molecular Biology

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This renewal proposal seeks to further characterize the molecular mechanisms involved in the loss of specific brain cells in common Alzheimer's disease (AD). Over the recent years, our laboratory has documented a complex mechanism that controls the synthe
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