Neurons' electrical activity refines neural circuits by strengthening the connections between neurons with correlated activity while eliminating connections between neurons with uncorrelated activity.

神经元的电活动通过加强具有相关活动的神经元之间的连接同时消除具有不相关活动的神经元之间的连接来细化神经回路。

• 批准号: 273582
• 负责人: Gharat Amol
• 金额: $ 10.93万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-11-01 至 2015-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=273582&lang=en
• 关键词: Confocal Imaging; Electrophysiology; Neural Circuits; Neural Plasticity; Synaptic Activity

During early postnatal life, neural circuits undergo reorganization in which some connections are strengthened while others are eliminated to form efficient circuits. However, we know little about the mechanism underlying this refinement process. Previous

在出生后的早期，神经回路经历重组，其中一些连接得到加强，而另一些连接被消除以形成有效的回路。然而，我们对这种细化过程的机制知之甚少。先前