冷冻电子显微镜分析脂质调节人表皮生长因子受体（EGFR）的结构基础-猫眼课题宝

冷冻电子显微镜分析脂质调节人表皮生长因子受体（EGFR）的结构基础

批准号：

281179

负责人：

Kim Kelly

金额：

$10.93万

依托单位：

Harvard Medical School (Boston, Massachusetts)

依托单位国家：

加拿大

项目类别：

Fellowship Programs

财政年份：

2013

资助国家：

加拿大

项目状态：

已结题

起止时间：

2013-02-01 至 2016-02-01

来源：

https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=281179&lang=en

关键词：

Cancer Cell Signalling Cryo-Electron Microscopy Epidermal Growth Factor Receptor Lipid Membrane Protein Nanodisc Protein Expression Protein Purification

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英文摘要

Membrane proteins are responsible for many essential cellular processes and their dysfunction often results in diseases, including many types of cancer. Membrane proteins are therefore of great biomedical interest, but realizing their potential as drug ta

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海外基金

Cryo-electron Microscopic Analysis of the Structural Basis for the Regulation of Human Epidermal Growth Factor Receptor (EGFR) by Lipids

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