Large Field of View, High Resolution Multi Worm Tracker

大视场、高分辨率多蠕虫追踪器

• 批准号: 458630-2014
• 负责人: Rankin, Catharine
• 金额: $ 1.65万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=541990
• 关键词: Large; Field; View; Resolution; Multi

This application is for funds to build a tracking system that will electronically track the behaviour of a large number of microscopic organisms at the same time. This will allow researchers to study more animals in greater detail and in a shorter time period than existing methods. Understanding the behaviour in more detail greatly facilitates investigations of neural and genetic mechanisms of behaviour. The camera we are requesting has a much larger field of view at a high resolution than our existing set-ups. This will allow us to study both smaller and larger animals than we are currently using. This means that in addition to studying the behaviour of a microscopic nematode worm, we will be able to study Drosophila larvae and frog tadpoles. This work will allow us to expand our collaborations with researchers at UBC, and at a number of universities in Canada and in the United States. This, in turn, will increase the training opportunities in my lab for both graduate students and undergraduate students. Graduate students will benefit from the interdisciplinary nature of the collaborations, while undergraduates will get opportunities to collect original data and experience a research project from beginning to end. For the graduate students the collaborations offer them insights into how other types of problems are studied and often gives them new "tool" or techniques that they can apply in their own work. This type of experience allows undergraduates to decide if they wish to pursue research as a career, or not. For students going on to other professions such as medicine, dentistry and speech pathology, the research experience offers them an understanding of how research is done and a way to interpret the scientific studies underlying their applied professions.

这项申请是为建立一个跟踪系统的资金，该系统将同时以电子方式跟踪大量微生物的行为。这将使研究人员能够在比现有方法更详细、更短的时间内研究更多的动物。更详细地了解这些行为，极大地促进了对行为的神经和遗传机制的研究。我们要求的相机在高分辨率下的视野比我们现有的设置要大得多。这将使我们能够研究比我们目前使用的更小和更大的动物。这意味着，除了研究微小线虫的行为外，我们还将能够研究果蝇幼虫和青蛙蝌蚪。这项工作将使我们能够扩大与UBC以及加拿大和美国多所大学的研究人员的合作。反过来，这将增加我的实验室对研究生和本科生的培训机会。研究生将从合作的跨学科性质中受益，而本科生将有机会收集原始数据，从头到尾体验一个研究项目。对于研究生来说，这些合作为他们提供了如何研究其他类型问题的洞察力，并经常为他们提供新的“工具”或技术，他们可以在自己的工作中应用。这种类型的经历允许本科生决定是否希望将研究作为一种职业。对于医学、牙科和语言病理学等其他专业的学生来说，研究经历让他们了解研究是如何进行的，并提供了一种解释其应用职业背后的科学研究的方法。