Co-development of a comprehensive cell-culture bioreactor

共同开发综合细胞培养生物反应器

• 批准号: 458974-2013
• 负责人: Tang, XiaowuShirley
• 金额: $ 1.65万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=542108
• 关键词: Co; development; comprehensive; cell; culture

This proposal is for the co-development of a cell-culture bioreactor by Tang's BIONANO lab at University of Waterloo and its industrial partner, CellScale Biomaterials Testing. The goal is to modify CellScale's existing product, MechanoCulture, and interface the modified devices with external electronics to make comprehensive bioreactors capable of electrical stimulation and perfusion during cell culture, in addition to mechanical exercise. Such bioreactors are highly sought after by researchers in the tissue engineering and regenerative medicine fields, but not yet commercially available. This project is the first joint R&D effort between the Tang lab and CellScale. The two parties will work together to design, fabricate, and test the modified MechanoCulture systems. At the project end, the new design and operation parameters will be validated in the Tang lab and transferred to CellScale for commercialization. Plus, the Tang lab will continue to use the developed devices to carry out cutting edge tissue engineering projects.

该提案是由滑铁卢大学的Tang's BIONANO实验室及其工业合作伙伴CellScale Biomaterials Testing共同开发的细胞培养生物反应器。其目标是修改CellScale现有的产品MechanoCulture，并将修改后的设备与外部电子设备连接，以使综合生物反应器能够在细胞培养期间进行电刺激和灌注，以及机械运动。这种生物反应器受到组织工程和再生医学领域研究人员的高度追捧，但尚未商业化。该项目是Tang实验室和CellScale之间的第一个联合研发项目。双方将共同设计、制造和测试改良后的机械培养系统。项目结束时，新的设计和操作参数将在Tang实验室进行验证，并转移到CellScale进行商业化。此外，Tang实验室将继续使用开发的设备进行尖端的组织工程项目。