Computer-based Decision Support for Management of Comorbid Diseases

基于计算机的共病疾病管理决策支持

• 批准号: 6776-2013
• 负责人: Michalowski, Wojtek
• 金额: $ 1.75万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=544377
• 关键词: Computer; based; Decision; Support; Management

A clinical practice guideline (CPG) is a knowledge-based tool for disease-specific patient management that encapsulates best practices in deriving at possible diagnoses, and prescribing the most appropriate treatment plan. However, the unmitigated concurrent application of disease-specific guidelines for comorbid patients often has undesired consequences due to the inconsistencies in the guidelines associated with adverse drug-drug or drug-disease interactions. Despite the clinical and social importance of managing patients with comorbid diseases, there is little research on the automatic mitigation of adverse interactions that might be present in concurrently used CPGs. The proposed research program is designed to fill the void.

临床实践指南(CPG)是一种基于知识的工具，用于特定疾病的患者管理，其中概括了在可能的诊断和开出最合适的治疗计划方面的最佳实践。然而，由于指南中与药物-药物或药物-疾病的不良相互作用相关的不一致，不加缓和地同时应用针对共病患者的特定疾病指南往往会产生不希望看到的后果。尽管管理合并疾病的患者具有临床和社会重要性，但关于自动缓解同时使用的CPG中可能存在的不良相互作用的研究很少。拟议的研究计划旨在填补这一空白。