Development of computer-based decision support tools using population pharmacokinetic/pharmacodynamic models

使用群体药代动力学/药效学模型开发基于计算机的决策支持工具

• 批准号: LP0990670
• 负责人: Prof Richard Day
• 金额: $ 22.28万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-03-31 至 2015-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP0990670
• 关键词: Development; computer; based; decision; support

Diabetes is an epidemic that presents an enormous burden to health systems of both developed and developing nations. Australia spends an estimated $35 billion on the condition annually, with costs set to rise with increasing diagnosis rates. Additionally, the burden of diabetes is more prominent in indigenous Australians. We intend to improve management of this disease in non-indigenous and indigenous Australians by development of a user-friendly computer-based decision support tool for doctors. Once established, this tool will have applications in other fields of health care where support is needed to make informed dosing decisions for critical medications and have the potential to reduce financial and social impacts of chronic disease.

糖尿病是一种流行病，对发达国家和发展中国家的卫生系统都构成了巨大的负担。澳大利亚每年在这种疾病上的支出估计为350亿美元，随着诊断率的提高，成本将会上升。此外，糖尿病的负担在澳大利亚土著居民中更为突出。我们打算通过为医生开发一个用户友好的基于计算机的决策支持工具来改善非土著和土著澳大利亚人对这种疾病的管理。一旦建立，这一工具将在卫生保健的其他领域得到应用，在这些领域，需要支持为关键药物做出知情的剂量决定，并有可能减少慢性病的经济和社会影响。