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Metal-organic compounds as scaffolds and libraries, for the exploration of biologically relevant chemical space.

Metal-organic compounds as scaffolds and libraries, for the exploration of biologically relevant chemical space.
金属有机化合物作为支架和库,用于探索生物相关的化学空间。
批准号:
326972-2013
负责人:
Luyt, Leonard
金额:
$2.48万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-01-01 至 2015-12-31

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英文摘要
The ability to create ligands with affinity for a protein target depends upon the presentation of functionality in specific locations of three dimensional space. Metal-based ligands have typically not been utilized for receptor targeting, and yet metal complexes have unique abilities in terms of addressing chemical space due to their higher coordination number and increased structural diversity. In addition, metal-organic ligands can be designed with features that are particularly valuable for combinatorial library screening and may be created to have fluorescent properties.
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Chemical Technology for Imaging Agent Discovery
  • 批准号:
    RGPIN-2018-05477
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $4.66万
  • 财政年份:
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  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $4.66万
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    2020
  • 负责人:
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  • 依托单位:
Chemical Technology for Imaging Agent Discovery
  • 批准号:
    RGPIN-2018-05477
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
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  • 财政年份:
    2019
  • 负责人:
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