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PTPN12: a key regulator of receptor-mediated signals and functions in immune cells and cancer cells

PTPN12: a key regulator of receptor-mediated signals and functions in immune cells and cancer cells
PTPN12：免疫细胞和癌细胞中受体介导的信号和功能的关键调节因子
批准号：
291086
负责人：
Veillette Andr
金额：
$53.33万
依托单位：
Institut de recherches cliniques de Montral
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-09-01 至 2018-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=291086&lang=en
关键词：
Immune Cells Phagocytosis Phosphatase Receptors Signaling Tumor Cells

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英文摘要
A type of enzyme that removes phosphates from other proteins is named "phosphatase". PTPN12 is one such enzyme. It is present inside all cells. Previous work showed that PTPN12 has the key role of controlling the ability of cells to move, attach and detac
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SLAMF7 in innate immune cells and anti-cancer immunotherapy
Targeting inhibitory immune checkpoints in macrophages for anti-cancer therapy
CRC Tier 1
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    364798
  • 项目类别：
  • 资助金额：
    $101.99万
  • 财政年份：
    2016
  • 负责人：
    Veillette Andr
  • 依托单位：
    Universit de Montral
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