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Targeting inhibitory immune checkpoints in macrophages for anti-cancer therapy

Targeting inhibitory immune checkpoints in macrophages for anti-cancer therapy
针对巨噬细胞中的抑制性免疫检查点进行抗癌治疗
批准号:
444655
负责人:
Veillette Andr
金额:
$69.66万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-04-01 至 2026-04-01

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中文摘要
翻译
在过去的10年里,癌症治疗中最重要的进展是“免疫疗法”的发展,特别是能够阻断PD-1和CTLA-4等分子的药物,这些分子可以抑制免疫细胞的功能,称为“T - c”
英文摘要
Over the past 10 years, the most significant advance in cancer treatment has been the development of "immunotherapy", in particular of agents capable of blocking molecules such as PD-1 and CTLA-4, which suppress the functions of immune cells known as "T c
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会议论文
SLAMF7 in innate immune cells and anti-cancer immunotherapy
CRC Tier 1
  • 批准号:
    364798
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2016
  • 负责人:
    Veillette Andr
  • 依托单位:
SLAMF6 and 2B4: roles and modes of action in normal immunity and cancer immunotherapy
Genetic and molecular studies of lymphocyte activation, immunodeficiencies and autoimmunity
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