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Role and signaling mechanism of EAT-2, an adaptor involved in anti-tumor immunity

Role and signaling mechanism of EAT-2, an adaptor involved in anti-tumor immunity
抗肿瘤免疫接头蛋白EAT-2的作用及信号机制
批准号:
199519
负责人:
Veillette Andr
金额:
$61.22万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-03-01 至 2015-03-01

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中文摘要
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英文摘要
EAT-2 is a small molecule named "adaptor" that is expressed in cells of the immune system. A closely related protein, SAP, is mutated in boys suffering from X-linked lymphoproliferative (XLP) disease. Our recent work shows that the EAT-2 protein plays a c
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SLAMF7 in innate immune cells and anti-cancer immunotherapy
Targeting inhibitory immune checkpoints in macrophages for anti-cancer therapy
CRC Tier 1
  • 批准号:
    364798
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2016
  • 负责人:
    Veillette Andr
  • 依托单位:
SLAMF6 and 2B4: roles and modes of action in normal immunity and cancer immunotherapy
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