Role and signaling mechanism of EAT-2, an adaptor involved in anti-tumor immunity
抗肿瘤免疫接头蛋白EAT-2的作用及信号机制
基本信息
- 批准号:199519
- 负责人:
- 金额:$ 61.22万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2010
- 资助国家:加拿大
- 起止时间:2010-03-01 至 2015-03-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
EAT-2 is a small molecule named "adaptor" that is expressed in cells of the immune system. A closely related protein, SAP, is mutated in boys suffering from X-linked lymphoproliferative (XLP) disease. Our recent work shows that the EAT-2 protein plays a c
EAT-2是一种名为“适配器”的小分子,在免疫系统细胞中表达。一种密切相关的蛋白SAP在患有x连锁淋巴细胞增生性疾病(XLP)的男孩中发生突变。我们最近的工作表明,EAT-2蛋白在c
项目成果
期刊论文数量(0)
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{{ truncateString('Veillette Andr', 18)}}的其他基金
SLAMF7 in innate immune cells and anti-cancer immunotherapy
SLAMF7在先天免疫细胞和抗癌免疫治疗中的作用
- 批准号:
462235 - 财政年份:2022
- 资助金额:
$ 61.22万 - 项目类别:
Operating Grants
Targeting inhibitory immune checkpoints in macrophages for anti-cancer therapy
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444655 - 财政年份:2021
- 资助金额:
$ 61.22万 - 项目类别:
Operating Grants
SLAMF6 and 2B4: roles and modes of action in normal immunity and cancer immunotherapy
SLAMF6和2B4:在正常免疫和癌症免疫治疗中的作用和作用方式
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343109 - 财政年份:2016
- 资助金额:
$ 61.22万 - 项目类别:
Operating Grants
Genetic and molecular studies of lymphocyte activation, immunodeficiencies and autoimmunity
淋巴细胞活化、免疫缺陷和自身免疫的遗传和分子研究
- 批准号:
312174 - 财政年份:2014
- 资助金额:
$ 61.22万 - 项目类别:
Operating Grants
Harnessing the SLAM-SAP pathways to improve immune surveillance against cancer
利用 SLAM-SAP 途径改善癌症免疫监视
- 批准号:
284564 - 财政年份:2013
- 资助金额:
$ 61.22万 - 项目类别:
Operating Grants
10th Conference on Signalling in Normal and Cancer Cells
第十届正常细胞和癌细胞信号转导会议
- 批准号:
289651 - 财政年份:2013
- 资助金额:
$ 61.22万 - 项目类别:
Miscellaneous Programs
PTPN12: a key regulator of receptor-mediated signals and functions in immune cells and cancer cells
PTPN12:免疫细胞和癌细胞中受体介导的信号和功能的关键调节因子
- 批准号:
291086 - 财政年份:2013
- 资助金额:
$ 61.22万 - 项目类别:
Operating Grants
Receptors controlling natural killer cell functions in anti-tumor immunity
控制抗肿瘤免疫中自然杀伤细胞功能的受体
- 批准号:
238251 - 财政年份:2011
- 资助金额:
$ 61.22万 - 项目类别:
Operating Grants
9th Conference on Signalling in Normal and Cancer Cells
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- 批准号:
215780 - 财政年份:2010
- 资助金额:
$ 61.22万 - 项目类别:
Miscellaneous Programs
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