The effect of cortical interactions on motor output by the primary motor cortex

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The primary motor cortex (M1) plays a pivotal role in the control of forelimb movements in primates. M1 receives numerous inputs from other cortical areas, in particular from the premotor cortices and the primary somatosensory cortex (S1). Currently, little is known on how these cortical connections contribute to the planning and regulation of movements. The general objective of our research program is to investigate the influence of cortical inputs from distant cortical areas on M1 and the role of these areas in the control of hand and arm movements. In the present set of experiments, we will focus on the topographic specificity of cortical inputs in M1 and how these inputs modulate the corticospinal outputs of M1.