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Targeting mitochondrial translation as a novel therapeutic strategy for AML

Targeting mitochondrial translation as a novel therapeutic strategy for AML
靶向线粒体翻译作为 AML 的新型治疗策略
批准号:
289699
负责人:
Schimmer Aaron D
金额:
$59.74万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-09-01 至 2018-09-01

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中文摘要
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英文摘要
AML (acute myeloid leukemia) is a disease with a poor outcome for which new therapeutic agents are needed. To identify new treatment strategies for AML, we screened a large chemical library of old drugs and identified tigecycline, a drug used for treatme
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会议论文
The IL23 Receptor (IL23R) regulates mitotic spindle formation and is a novel therapeutic target for AML
  • 批准号:
    483377
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2023
  • 负责人:
    Schimmer Aaron D
  • 依托单位:
Improved treatments of Acute Myeloid Leukaemias by Personalized Medicine
  • 批准号:
    387780
  • 项目类别:
    Operating Grants
  • 资助金额:
    $32.78万
  • 财政年份:
    2018
  • 负责人:
    Schimmer Aaron D
  • 依托单位:
Developing new therapeutic strategies for AML (Acute Myeloid Leukemia)
  • 批准号:
    354022
  • 项目类别:
    Operating Grants
  • 资助金额:
    $242.84万
  • 财政年份:
    2016
  • 负责人:
    Schimmer Aaron D
  • 依托单位:
Targeting mitochondrial protein folding in the inter-membrane space as a novel therapeutic strategy for AML
  • 批准号:
    354325
  • 项目类别:
    Operating Grants
  • 资助金额:
    $52.94万
  • 财政年份:
    2016
  • 负责人:
    Schimmer Aaron D
  • 依托单位:
国内基金
海外基金
一碳代谢(One carbon metabolism)介导上调的 PD1/PDL1 驱动 肿瘤免疫逃逸
  • 批准号:
    2024JJ9491
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    彭罗根
  • 依托单位: