Targeting the mitochondrial proteasome, ClpP, in AML
Targeting the mitochondrial proteasome, ClpP, in AML
批准号:
303444
负责人:
Schimmer Aaron D
金额:
$51.54万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-03-01 至 2019-03-01
中文摘要
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英文摘要
The outcome for most patients with AML (acute myeloid leukemia) remains poor and new treatments for this disease are needed. Here, we propose to study the mitochondrial proteasome (ClpP) as a new therapeutic target for AML. The proteasome is like the ce
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