Effect of fungal toxins on fertility in dairy cattle

真菌毒素对奶牛繁殖力的影响

• 批准号: 430082-2012
• 负责人: Price, Christopher
• 金额: $ 3.05万
• 依托单位: Université de Montréal
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=552517
• 关键词: Effect; fungal; toxins; fertility; dairy

Cereals and grains used for animal feed can become contaminated with fungi, which release toxins into the feed. These toxins at low levels can have numerous deleterious effects on animal growth and reproduction. In cattle, contaminated feed can result in decreased ovarian activity and thus lower fertility. How fungal toxins decrease fertility in cattle is only partly understood. In Eastern Canada, the most common toxin is called DON, but the effect of this toxin on reproduction in ruminants has not been studied. In this research project, we will determine the effects of DON on ovarian function using a combination of in-vitro and in-vivo cattle models.

用于动物饲料的谷物和谷物可能会受到真菌的污染，真菌会向饲料中释放毒素。这些低水平的毒素会对动物的生长和繁殖产生许多有害的影响。在牛身上，受污染的饲料会导致卵巢活动减少，从而降低生育力。真菌毒素是如何降低牛的生育力的，人们对此只有部分了解。在加拿大东部，最常见的毒素是DON，但这种毒素对反刍动物生殖的影响尚未被研究。在这个研究项目中，我们将使用体外和体内牛模型相结合的方法来确定DON对卵巢功能的影响。