Implementing microfluidics-based manufacturing of model theranostic nanoparticles

实施基于微流体的模型治疗纳米颗粒制造

• 批准号: 430530-2012
• 负责人: Krull, Ulrich
• 金额: $ 6.12万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Strategic Projects - Group
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=552572
• 关键词: Implementing; microfluidics; based; manufacturing; model

Nanoparticles (NPs) are being exploited in the labeling of tissues and within cells for the detection and tracking of biological markers, chemical signals and dynamic cellular events. We have been contributing to the area of learning to build functional NPs for bioassays. We are now in a position to launch the next step of technology evolution where the bioanalytical detection system concurrently becomes a platform for delivery of a cargo such as a therapeutic agent. With our industry partner GL Chemtec, we will learn to manufacture such "theranostic" platforms, drawing on our joint strengths in synthesis at surfaces and in bioassay development.

纳米粒子（NP）被用于标记组织和细胞内的生物标记物，化学信号和动态细胞事件的检测和跟踪。我们一直致力于学习构建用于生物测定的功能性NP。我们现在能够启动技术发展的下一个步骤，其中生物分析检测系统同时成为递送货物（例如治疗剂）的平台。通过我们的行业合作伙伴GL Chemtec，我们将学习制造这种“治疗诊断”平台，利用我们在表面合成和生物测定开发方面的共同优势。