Functional analyses of 150 non-annotated genes in an industrial wine strain of saccharomyces cerevisiae

酿酒酵母工业酿酒菌株 150 个未注释基因的功能分析

• 批准号: 453128-2013
• 负责人: JansenvanVuuren, Hendrik
• 金额: $ 4.98万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=554982
• 关键词: Functional; analyses; 150; non; annotated

Saccharomyces cerevisiae responds transcriptionally to stress by general and/or stimuli-specific response mechanisms. We identified 62 non-annotated genes exhibiting sustained and dramatic induction (4 to 80-fold) during wine fermentation and named these genes the Fermentation Stress Response (FSR) genes. Over the past three years we have studied the biological functions of these 62 non-annotated S. cerevisiae FSR genes. We used a systems biology approach and have now successfully elucidated the functions of thee non-annotated FSR genes, which will lead to a patent.

酿酒酵母通过一般和/或刺激特异性应答机制对胁迫进行转录应答。我们确定了62个未注释的基因，这些基因在葡萄酒发酵过程中表现出持续和显著的诱导（4至80倍），并将这些基因命名为发酵应激反应（FSR）基因。在过去的三年里，我们研究了这62个未注释的S。酿酒酵母FSR基因。我们使用了系统生物学方法，现在已经成功地阐明了三个未注释的FSR基因的功能，这将导致专利。