The Role of Ethnic Racial Discrimination on the Development of Anxious Hypervigilance in Latina Youth

项目概要/摘要 威胁警戒有助于适应性防御反应，在真实的威胁的情况下是有利的。 然而，当极端和持续时，它会导致过度恐惧和逃避，这是焦虑的核心特征。 焦虑的理论模型表明，对威胁的过度警惕可能会引发，维持，甚至加剧 焦虑症状事实上，相对于健康的参与者，焦虑症患者表现出更大的心理生理 反应和失调的神经回路功能在许多威胁预期状态。是否以及如何 干扰受到威胁相关的心理社会因素的影响，如民族-种族（ER）歧视 和ER社会化，是不太好理解，特别是在青春期时，焦虑风险升高。到 为了弥补这一知识差距，目前的建议建立在现有的纵向研究的基础上， 社会经历加剧了8-13岁的前青春期拉丁女孩的焦虑过度警觉， 一组表现出高水平的未经治疗的焦虑，也有差异和过度暴露于ER 歧视本提案的具体目的是（1）了解ER歧视对 行为和神经生理学指标的焦虑过度警觉的拉丁美洲女孩，和（2）探讨主要和 父母ER社会化对焦虑性过度警觉的调节作用以及ER与焦虑性过度警觉之间的关系 歧视和焦虑过度警觉。将在两个月内评估焦虑过度警惕 基于任务的措施，通过社会判断的情感模糊的面孔刺激，同情和 副交感神经反应和神经活动。儿童焦虑症状，ER歧视和父母ER 将通过基于调查的措施对社会化进行评估。总之，通过这个项目，我将探索可能的 ER歧视和ER社会化的纵向、生物学和社会后遗症， ER社会化实践作为潜在的保护因素，增强了我对神经生理学和 纵向数据分析，并促进文化知情的干预和预防工作， 减少少数民族青年的焦虑。

Project Summary/Abstract Threat vigilance facilitates adaptive defensive responses and is advantageous in the case of real threats. However, when extreme and persistent, it can result in excessive fear and avoidance, core features of anxiety. Theoretical models of anxiety posit that hypervigilance towards threat may elicit, maintain, or even exacerbate anxiety symptoms. Indeed, relative to healthy participants, anxiety patients show greater psychophysiological responding and dysregulated neurocircuit function in many threat-anticipatory states. Whether and how such perturbations are impacted by threat-relevant psychosocial factors, such as ethnic-racial (ER) discrimination and ER socialization, is less well understood, particularly in adolescence when anxiety risk is elevated. To address this gap in knowledge, the current proposal builds on an existing longitudinal study to examine the social experiences that exacerbate anxious hypervigilance in preadolescent Latina girls aged 8-13 years, a group exhibiting high levels of untreated anxiety that is also differentially and excessively exposed to ER discrimination. The specific aims of this proposal are (1) to understand the effect of ER discrimination on behavioral and neurophysiological indices of anxious hypervigilance in Latina girls, and (2) to explore main and moderating effects of parental ER socialization on anxious hypervigilance and the association between ER discrimination and anxious hypervigilance, respectively. Anxious hypervigilance will be assessed during two task-based measures via social judgements of emotionally ambiguous face stimuli, sympathetic and parasympathetic responses, and neural activity. Child anxiety symptoms, ER discrimination, and parental ER socialization will be assessed via survey-based measures. In sum, through this project, I will explore possible longitudinal, biological, and social sequelae of ER discrimination and ER socialization, characterize parental ER socialization practices as potential protective factors, enhance my knowledge of neurophysiological and longitudinal data analysis, and contribute to culturally-informed intervention and prevention efforts aimed at reducing anxiety in minoritized youth.