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Discovery of novel molecular and pharmacological mechanisms in the ability of metformin to lower glucose production and blood glucose levels during diabetes

Discovery of novel molecular and pharmacological mechanisms in the ability of metformin to lower glucose production and blood glucose levels during diabetes
发现二甲双胍降低糖尿病期间葡萄糖产生和血糖水平能力的新分子和药理学机制
批准号：
297266
负责人：
Duca Frank A
金额：
$10.2万
依托单位：
University Health Network (Toronto)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-10-01 至 2015-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=297266&lang=en
关键词：
Anti-Diabetic Drugs Diabetes Endocrinology Gastroenterology Intestine Metabolism Metformin Nutrient-Sensing Nutrition Obesity

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英文摘要
Diabetes affects a staggering 347 million people worldwide, and in Canada alone, more than 9 million individuals are diabetic or pre-diabetic. As environmental factors continue to shift towards an obesogenic lifestyle, both obesity and diabetes rates will
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Mechanism of metformin action in the upper small intestine
  • 批准号：
    339164
  • 项目类别：
    Fellowship Programs
  • 资助金额：
    $3.28万
  • 财政年份：
    2015
  • 负责人：
    Duca Frank A
  • 依托单位：
    University Health Network (Toronto)
Discovery of a novel gastrointestinal signaling mechanism in the ability of metformin to lower glucose production and blood glucose levels during diabetes
  • 批准号：
    302099
  • 项目类别：
    Fellowship Programs
  • 资助金额：
    $3.28万
  • 财政年份：
    2013
  • 负责人：
    Duca Frank A
  • 依托单位：
    University Health Network (Toronto)
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