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Exploring the functional, structural, and behavioral determinants of repeated early-life stress exposure and the regulatory role of the endocannabinoid system

Exploring the functional, structural, and behavioral determinants of repeated early-life stress exposure and the regulatory role of the endocannabinoid system
探索生命早期反复压力暴露的功能、结构和行为决定因素以及内源性大麻素系统的调节作用
批准号：
300608
负责人：
McLaughlin Ryan J
金额：
$9.83万
依托单位：
Douglas Mental Health University Institute (Montreal, QC)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-11-01 至 2016-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=300608&lang=en
关键词：
Amygdala Dendritic Morphology Early Life Stress Endocannabinoid Signaling Fear Learning Hypothalamic-Pituitary-Adrenal Axis Immunohistochemistry In Situ Hybridization In Vitro Electrophysiology Prefrontal Cortex

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英文摘要
Exposure to stress during the first few weeks of life can have profound effects on brain development and how we process future stressful encounters. In rodents, early-life stressors such as prolonged separation from the mother produces exaggerated release
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Exploring the functional, structural, and behavioral determinants of repeated early-life stress exposure and the regulatory role of the endocannabinoid system
Prefrontocortical Cannabinoid Receptor Upregulation is Adaptive in an Animal Model of Depression
  • 批准号：
    184550
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2008
  • 负责人：
    McLaughlin Ryan J
  • 依托单位：
    University of British Columbia
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