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Production, chemistry and pharmacology of botanical anxiolytics and cortisol lowering agents for animal health market

Production, chemistry and pharmacology of botanical anxiolytics and cortisol lowering agents for animal health market
用于动物保健市场的植物抗焦虑药和皮质醇降低剂的生产、化学和药理学
批准号:
463303-2014
负责人:
Arnason, John
金额:
$3.5万
依托单位:
依托单位国家:
加拿大
项目类别:
Collaborative Research and Development Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-01-01 至 2015-12-31

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中文摘要
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英文摘要
Based on phytochemical discovery research, our team has successfully launched the Sin SustoTM anxiolytic product, an allopathic natural health product for Vet application as a calming and cortisol lowering agent in dogs. Feedback from veterinarians and our own data, indicates that new research is needed to answer aspects of quality assurance (agronomic and phytochemical standardization) safety evaluation (pharmacokinetics, pharmacodynamics, drug interactions) and mode of action ( pharmacology). The discovery of the cortisol lowering activity of the active principle, betulinic acid, provides a lead compound for semi synthesis of a pipeline of potential pharmaceuticals for evaluation and application in Cushings disease and metabolic syndrome.
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  • 批准号:
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  • 项目类别:
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  • 财政年份:
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  • 批准号:
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