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Cellular Bioenergetics in Neurodegenerative Diseases: A system-based pathway and target analysis.

Cellular Bioenergetics in Neurodegenerative Diseases: A system-based pathway and target analysis.
神经退行性疾病中的细胞生物能学:基于系统的途径和目标分析。
批准号:
314192
负责人:
Park David S
金额:
$36.42万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-06-01 至 2017-06-01

项目摘要

项目成果

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中文摘要
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英文摘要
Increasing evidence suggests that mitochondria, a part of the cell which generates energy, are damaged in neurodegenerative diseases including PD and AD. How this dysfunction contributes to brain cell loss is unclear. Our current proposal will determine
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Novel pathways underlying degeneration in Parkinson's disease: a focus on Pink1 and LRRK2
  • 批准号:
    341920
  • 项目类别:
    Operating Grants
  • 资助金额:
    $69.62万
  • 财政年份:
    2016
  • 负责人:
    Park David S
  • 依托单位:
Defining critical pathways for neuronal loss and dysfunction in Parkinsons disease and stroke
  • 批准号:
    333139
  • 项目类别:
    Operating Grants
  • 资助金额:
    $254.97万
  • 财政年份:
    2015
  • 负责人:
    Park David S
  • 依托单位:
GBA1 mutations in Parkinson's disease: clinical and biochemical prodrome, risk profile and pathogenetic modelling for therapeutic intervention.
  • 批准号:
    332703
  • 项目类别:
    Operating Grants
  • 资助金额:
    $24.26万
  • 财政年份:
    2015
  • 负责人:
    Park David S
  • 依托单位:
Insights into Parkinson's disease, Crohn's disease, and leprosy: a common role for LRRK2
  • 批准号:
    296663
  • 项目类别:
    Operating Grants
  • 资助金额:
    $178.01万
  • 财政年份:
    2013
  • 负责人:
    Park David S
  • 依托单位:
海外基金