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Mechanisms of Lymphocytes Transmigration Across the Blood Brain Barrier

Mechanisms of Lymphocytes Transmigration Across the Blood Brain Barrier
淋巴细胞跨血脑屏障的迁移机制
批准号：
313936
负责人：
Prat Alexandre
金额：
$8.2万
依托单位：
Centre hospitalier de l'Universit de Montral (CHUM)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2014
资助国家：
加拿大
项目状态：
已结题
起止时间：
2014-06-01 至 2017-06-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=313936&lang=en
关键词：
Alzheimer'S Disease Blood-Brain Barrier Lymphocytes Multiple Sclerosis Neuroimmunology Stroke

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中文摘要
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英文摘要
Many diseases of the central nervous system (CNS) show strong involvement of cells of the immune system, and are therefore considered inflammatory diseases of the CNS. Among these diseases are included multiple sclerosis (MS), Alzheimer's disease (AD) and
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Canada Research Chair - Tier 1
  • 批准号：
    471059
  • 项目类别：
  • 资助金额：
    $101.99万
  • 财政年份：
    2022
  • 负责人：
    Prat Alexandre
  • 依托单位：
    Universit de Montral
Integrin Alpha8 is a novel mediator of T lymphocyte migration across the CNS barriers
A transgenic mouse model of multiple sclerosis offers new ways to identify mechanisms of progression and novel therapies
Integrin alpha8 is a novel mediator of pro-inflammatory T lymphocyte migration across the CNS barriers
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