The regenerative effects of the trophic cytokines granulocyte macrophage-colony stimulating factor and erythropoietin in murine model of Parkinson's disease.

营养细胞因子粒细胞巨噬细胞集落刺激因子和促红细胞生成素在帕金森病小鼠模型中的再生作用。

• 批准号: 332333
• 负责人: Farmer Kyle
• 金额: $ 7.65万
• 依托单位: Carleton University (Ottawa)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-10-01 至 2017-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=332333&lang=en
• 关键词: 6-Hydroxydopamine; Behavioral Outcomes; Biomarkers; Erythropoietin; Granulocyte Macrophage-Colony Stimulating Factor; Immune System Modulation; In Vitro And In Vivo Analysis; Parkinson'S Disease; Prodromal/Early Stages; Subcellular Mechanism Determination

Parkinson's disease (PD) is a devastating age-related neurodegenerative disease which results in debilitating motor deficits. By the time of motor symptom presentation, there has already been a significant loss of midbrain neurons. Current treatments only

帕金森氏病(PD)是一种破坏性的与年龄相关的神经退行性疾病，会导致衰弱的运动障碍。到出现运动症状时，中脑神经元已经显著丧失。仅限当前治疗