The effect of lyophilization on the structure of bone morphogenetic protein

冻干对骨形态发生蛋白结构的影响

• 批准号: 477274-2014
• 负责人: Yip, Christopher
• 金额: $ 1.82万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=565727
• 关键词: effect; lyophilization; structure; bone; morphogenetic

The physical, chemical, electronic, and in some cases, biological properties of a material are inherently tied to the molecular structure and conformation of its constituents. Understanding how manufacturing processes, including storage and reconstitution, may impact these characteristics is critical to the ultimate end-use application, including in some cases biocompatibility and performance.

材料的物理、化学、电子以及某些情况下的生物特性本质上与其成分的分子结构和构象相关。了解制造工艺（包括存储和重构）如何影响这些特性对于最终的最终用途应用至关重要，包括在某些情况下的生物相容性和性能。