Functional polymers and networks
功能聚合物和网络
基本信息
- 批准号:89661-2011
- 负责人:
- 金额:$ 6.19万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2015
- 资助国家:加拿大
- 起止时间:2015-01-01 至 2016-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
We study the formation of polymers and polymer networks with interesting structures and properties. For example, we use precipitation polymerization of crosslinking monomers in select solvents to form clean, mono-disperse microspheres of 2 to 18 micrometer diameter, that are colloidally stabilized by the ongoing deposition of new polymer nanogels. We are learning how to use this sequential, layer-by-layer growth process to inscribe layers of unique structure and composition, using thermal cycling as well as injection of co-monomers, during particle growth. This results in direct formation of multi-layered microspheres with defined onion structures.
We also study polymer network formation at oil-water interfaces. We learned how to stabilize oil emulsions in water using silica nanoparticles of the correct polarity, instead of soluble surfactants. We now are using similar, chemically modified nanoparticles to form polymeric shells to strengthen the resulting capsules and make them useful for controlled release applications.
Finally, we are developing reactive polyelectrolytes that spontaneously combine in aqueous conditions to form crosslinked hydrogels. The ultimate use of these hydrogels is for the encapsulation and immuno-isolation of cells designed to secrete hormones such as insulin, and hence serve as transplantable, cell-based cures for i.e. diabetes. Here, we are are exploring fundamental chemical properties of these novel hydrogel formers, including crosslink chemistry, persistence to hydrolysis, and ease of modification with compatibility-enhancing modifiers such as polyethyleneglycol.
我们研究具有有趣结构和性质的聚合物和聚合物网络的形成。例如,我们使用交联剂单体在选定的溶剂中进行沉淀聚合,形成直径为2至18微米的清洁、单分散的微球,通过不断沉积新的聚合物纳米凝胶来实现胶体稳定。我们正在学习如何使用这种顺序的、逐层生长的过程,在颗粒生长过程中使用热循环和注入共聚单体来刻写具有独特结构和组成的层。这导致直接形成具有定义的洋葱结构的多层微球。
我们还研究了油水界面聚合物网络的形成。我们学习了如何使用正确极性的二氧化硅纳米颗粒而不是可溶性表面活性剂来稳定水中的油乳剂。我们现在正在使用类似的、经过化学修饰的纳米颗粒来形成聚合物外壳,以加强所产生的胶囊,使其用于控制释放应用。
最后,我们正在开发在水条件下自发结合形成交联型水凝胶的反应性聚电解质。这些水凝胶的最终用途是对旨在分泌胰岛素等激素的细胞进行封装和免疫隔离,从而作为可移植的、基于细胞的糖尿病治疗方法。在这里,我们正在探索这些新型水凝胶成形剂的基本化学性质,包括交联性、耐水解性以及易于使用增容改性剂如聚乙二醇改性。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Stöver, Harald其他文献
Stöver, Harald的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Stöver, Harald', 18)}}的其他基金
Improving Cell Encapsulation by Detection and Mitigation of Protruding Cells
通过检测和减轻突出细胞来改善细胞封装
- 批准号:
509228-2017 - 财政年份:2017
- 资助金额:
$ 6.19万 - 项目类别:
Engage Grants Program
NSERC CREATE Integrated Design of Extracellular Matrices (IDEM)
NSERC CREATE 细胞外基质综合设计 (IDEM)
- 批准号:
398058-2011 - 财政年份:2016
- 资助金额:
$ 6.19万 - 项目类别:
Collaborative Research and Training Experience
NSERC CREATE Integrated Design of Extracellular Matrices (IDEM)
NSERC CREATE 细胞外基质综合设计 (IDEM)
- 批准号:
398058-2011 - 财政年份:2015
- 资助金额:
$ 6.19万 - 项目类别:
Collaborative Research and Training Experience
NSERC CREATE Integrated Design of Extracellular Matrices (IDEM)
NSERC CREATE 细胞外基质综合设计 (IDEM)
- 批准号:
398058-2011 - 财政年份:2014
- 资助金额:
$ 6.19万 - 项目类别:
Collaborative Research and Training Experience
Functional polymers and networks
功能聚合物和网络
- 批准号:
89661-2011 - 财政年份:2014
- 资助金额:
$ 6.19万 - 项目类别:
Discovery Grants Program - Individual
NSERC CREATE Integrated Design of Extracellular Matrices (IDEM)
NSERC CREATE 细胞外基质综合设计 (IDEM)
- 批准号:
398058-2011 - 财政年份:2013
- 资助金额:
$ 6.19万 - 项目类别:
Collaborative Research and Training Experience
Functional polymers and networks
功能聚合物和网络
- 批准号:
89661-2011 - 财政年份:2013
- 资助金额:
$ 6.19万 - 项目类别:
Discovery Grants Program - Individual
NSERC CREATE Integrated Design of Extracellular Matrices (IDEM)
NSERC CREATE 细胞外基质综合设计 (IDEM)
- 批准号:
398058-2011 - 财政年份:2012
- 资助金额:
$ 6.19万 - 项目类别:
Collaborative Research and Training Experience
Functional polymers and networks
功能聚合物和网络
- 批准号:
89661-2011 - 财政年份:2012
- 资助金额:
$ 6.19万 - 项目类别:
Discovery Grants Program - Individual
NSERC CREATE Integrated Design of Extracellular Matrices (IDEM)
NSERC CREATE 细胞外基质综合设计 (IDEM)
- 批准号:
398058-2011 - 财政年份:2011
- 资助金额:
$ 6.19万 - 项目类别:
Collaborative Research and Training Experience
相似国自然基金
用于小尺寸管道高分辨成像荧光聚合物点的构建、成像机制及应用研究
- 批准号:82372015
- 批准年份:2023
- 资助金额:48.00 万元
- 项目类别:面上项目
用于非富勒烯聚合物太阳能电池的苯并三氮唑类二维共轭聚合物
- 批准号:51673200
- 批准年份:2016
- 资助金额:65.0 万元
- 项目类别:面上项目
超支化共轭聚合物的合成、表征和性质研究
- 批准号:20574075
- 批准年份:2005
- 资助金额:27.0 万元
- 项目类别:面上项目
含重过渡与稀土元素的多金属配合物的磁、光性质研究
- 批准号:20371027
- 批准年份:2003
- 资助金额:26.0 万元
- 项目类别:面上项目
相似海外基金
Collaborative Research: DMREF: Closed-Loop Design of Polymers with Adaptive Networks for Extreme Mechanics
合作研究:DMREF:采用自适应网络进行极限力学的聚合物闭环设计
- 批准号:
2413579 - 财政年份:2024
- 资助金额:
$ 6.19万 - 项目类别:
Standard Grant
Collaborative Research: DMREF: Closed-Loop Design of Polymers with Adaptive Networks for Extreme Mechanics
合作研究:DMREF:采用自适应网络进行极限力学的聚合物闭环设计
- 批准号:
2323727 - 财政年份:2023
- 资助金额:
$ 6.19万 - 项目类别:
Standard Grant
Collaborative Research: DMREF: Closed-Loop Design of Polymers with Adaptive Networks for Extreme Mechanics
合作研究:DMREF:采用自适应网络进行极限力学的聚合物闭环设计
- 批准号:
2323728 - 财政年份:2023
- 资助金额:
$ 6.19万 - 项目类别:
Standard Grant
Discovery and characterization of bacterial cell envelope assembly and remodeling networks that modulate tolerance to antibiotics
调节抗生素耐受性的细菌细胞包膜组装和重塑网络的发现和表征
- 批准号:
10711329 - 财政年份:2023
- 资助金额:
$ 6.19万 - 项目类别:
Collaborative Research: DMREF: Closed-Loop Design of Polymers with Adaptive Networks for Extreme Mechanics
合作研究:DMREF:采用自适应网络进行极限力学的聚合物闭环设计
- 批准号:
2323731 - 财政年份:2023
- 资助金额:
$ 6.19万 - 项目类别:
Standard Grant
Effect of disorder on polymers and on real-world networks
无序对聚合物和现实世界网络的影响
- 批准号:
23K12984 - 财政年份:2023
- 资助金额:
$ 6.19万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Collaborative Research: DMREF: Closed-Loop Design of Polymers with Adaptive Networks for Extreme Mechanics
合作研究:DMREF:采用自适应网络进行极限力学的聚合物闭环设计
- 批准号:
2323729 - 财政年份:2023
- 资助金额:
$ 6.19万 - 项目类别:
Standard Grant
Collaborative Research: DMREF: Closed-Loop Design of Polymers with Adaptive Networks for Extreme Mechanics
合作研究:DMREF:采用自适应网络进行极限力学的聚合物闭环设计
- 批准号:
2323730 - 财政年份:2023
- 资助金额:
$ 6.19万 - 项目类别:
Standard Grant
Zwitterionic Polymers-based Metal Phenolic Networks as Removable Protein Protectants
基于两性离子聚合物的金属酚醛网络作为可去除的蛋白质保护剂
- 批准号:
23K17211 - 财政年份:2023
- 资助金额:
$ 6.19万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
The surface-confined formation of self-assembled molecular networks and 2D polymers
自组装分子网络和二维聚合物的表面限制形成
- 批准号:
573355-2022 - 财政年份:2022
- 资助金额:
$ 6.19万 - 项目类别:
University Undergraduate Student Research Awards