Controlled Structuring of Heterophase Biopolymers at the Micro and Nano Scale

微米和纳米尺度异相生物聚合物的受控结构

• 批准号: 90521-2012
• 负责人: Favis, Basil
• 金额: $ 3.64万
• 依托单位: École Polytechnique de Montréal
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=569011
• 关键词: Controlled; Structuring; Heterophase; Biopolymers; Micro

The use of biopolymers has seen dramatic growth in the last decade. Although the escalation of biopolymers' use is impressive, the materials presently on the market suffer from a range of systemic performance weaknesses and these weaknesses currently represent barriers to their sustained growth worldwide. The blending of biopolymers to generate heterophase systems is considered to be one of the main approaches to overcome these inherent property limitations. In this project we will concentrate on micro- and nano-phase structuring through morphology and interface control in multiphase biopolymer systems as a route towards the development of next-generation biomaterials. Thermodynamically stable ternary, quaternary and quinary biopolymer systems will be studied. Co-continuous morphologies and encapsulated droplet-in-droplet structures are sophisticated microstructures which can be used to develop completely new property sets as compared to the classical droplet-in-matrix type systems. The controlled localization of nanoinclusions within these multiphase biopolymer systems and the potential of such a system for conductive applications will be examined. The transformation of these complex structures into porous materials and their potential for controlled drug release will also be explored.

生物聚合物的使用在过去十年中出现了急剧增长。虽然生物聚合物的升级 使用是令人印象深刻的，目前市场上的材料遭受一系列的系统性能 这些弱点目前是它们在全球持续增长的障碍。的 将生物聚合物共混以产生多相体系被认为是 克服这些固有的属性限制。在这个项目中，我们将专注于通过多相生物聚合物系统中的形态和界面控制来实现微米和纳米相结构，作为开发下一代生物材料的途径。热力学稳定的三元，四元和五元生物聚合物系统将进行研究。共连续形态和包封的液滴中液滴结构是复杂的微结构，与经典的液滴中基质型系统相比，其可用于开发全新的性质集。将检查这些多相生物聚合物系统内的纳米夹杂物的控制定位和这种系统的导电应用的潜力。这些复杂的结构转化成多孔材料和控制药物释放的潜力也将被探索。